![]() ![]() Due to cross-reaction with other flaviviruses and possible nonspecific reactivity, results may be difficult to interpret.Patients with a change from negative to positive IgM results in paired samples (first sample collected during the first 7 days of illness, and second sample collected after symptoms subside) are classified as current dengue infections.Patients with negative IgM results after 7 days of symptoms, and absent or negative NAAT or NS1 (dengue virus antigen detection) are classified as negative for recent infection.For these cases, a second sample should be obtained after day 7 of symptoms for additional serologic testing. Patients with negative IgM results before day 8 of illness and absent or negative NAAT or NS1 results are considered unconfirmed cases.Positive IgM: Patients with a positive IgM test result are classified as presumptive, recent dengue virus infections.*Some IgM tests can be performed on plasma and whole blood but these tests have not been extensively evaluated for these specimen types. ![]()
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